BIOS Scientific Publishers Limited, 2000
First published 1997
Second edition published 2000
All rights reserved. No part of this book may be reproduced or transmitted, in any form or
by any means, without permission.
A CIP catalogue record for this book is available from the British Library.
ISBN 1 85996 142 8
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Cover image: molecular surface rendering of HIV-1 reverse transcriptase complexed with a highly specific RNA
pseudoknot inhibitor (J. Jaeger et al. EMBO J. 17(15): 4535–42, 1988). The inhibitor was generated by SELEX
method and has a sub-nanomolar binding constant. Image courtesy of Dr. J. Jaeger, Astbury Centre for Structural
Molecular Biology, University of Leeds.
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